Kaul Pediatric Research Institute (KPRI)

Initially known as the Pediatric Research Institute, the Kaul Pediatric Research Institute (KPRI) was created by the Board of Trustees of Children’s of Alabama in 1989 to provide internal funding for junior faculty who were just beginning their academic careers. The initial funding came from proceeds (10%) of the Children’s Miracle Network telethon, with half committed to an endowment and the other half to support grants submitted by faculty or professionals working at Children’s of Alabama. The first grants were awarded in 1993. Following the donation of an initial $5 million from the Kaul Foundation to increase the endowment, the Board of Trustees changed the name of this program to the Kaul Pediatric Research Institute (KPRI).

 

KPRI Grant Program

Initially, four two-year grants of $20,000 per year were awarded. With the increase of the contributions to the KPRI and the growth of the endowment, multiple awards are made each year in the amount of $35,000 each for new investigators and $50,000 each for established investigators.

The program is competitive and peer-reviewed in an NIH format. Since 2008, $4,940,000 has been awarded for biomedical research. This represents 72 unique investigators receiving 82 awards, including 16 established investigator awards and 66 new investigator awards. KPRI recipients have received almost $60.7 million in funding. Of these 65 investigators, 53 remain at UAB.

The major goal of the KPRI grant program is to allow investigators to obtain data that will advantage applications for additional extramural funding. This will bring new knowledge to the care of children, leverage the investment of the KPRI, and allow projects to be competitive for the very best science on the national stage. A second, but important, goal is to ensure that a dedicated funding source is available to unique segments of the pediatric research and education.

2021 Awards

New Investigator Awards

Pallavi Iyer, M.D.
Associate Professor
Division of Pediatric Endocrinology & Diabetes
Project title: Integrative Genomic Characterization of Pediatric Differentiated Thyroid Cancer

Claudette Poole, M.D.
Assistant Professor
Division of Pediatric Infectious Diseases
Project title: The Association of SARS-CoV-2 Infection and Diabetes Mellitus in Children

Emily Smitherman, M.D.
Assistant Professor
Division of Pediatric Rheumatology
Project title: Evaluating Access to Care in Childhood-onset Systemic Lupus Erythematosus Nephritis

Viral Jain, M.D.
Assistant Professor
Division of Neonatology
Project title: Chorioamnionitis Leads to Altered Neonatal Immune System Development

Brandon Rocque, M.D.
Associate Professor
Division of Pediatric Neurosurgery
Project title: Traumatic Stress and Shunt Failure: A Link between Psychology and Inflammation

Kent Willis, M.D.
Assistant Professor
Division of Neonatology
Project title: The Mycobiome Shapes Oxygen Exposure Lung Injury in Newborns via the Chitin Binding Receptor FIBCDl

Established Investigator Award

William Britt, M.D.
Professor
Division of Pediatric Infectious Diseases
Project title: Seasonal Coronavirus Infections and Antibody Responses to SARS-CoV-2

Randy Cron, M.D.
Professor
Division of Pediatric Rheumatology
Project title: Functional Genomics of Novel Cytokine Storm Syndrome Genes Linked with SARS-CoV- 2

2021 KPRI Quality Safety Awards

Initially, four two-year grants of $20,000 per year were awarded. With the increase of the contributions to the KPRI and the growth of the endowment, multiple awards are made each year in the amount of $35,000 each for new investigators and $50,000 each for established investigators.

The program is competitive and peer-reviewed in an NIH format. Since 2008, $4,940,000 has been awarded for biomedical research. This represents 72 unique investigators receiving 82 awards, including 16 established investigator awards and 66 new investigator awards. KPRI recipients have received almost $60.7 million in funding. Of these 65 investigators, 53 remain at UAB.

The major goal of the KPRI grant program is to allow investigators to obtain data that will advantage applications for additional extramural funding. This will bring new knowledge to the care of children, leverage the investment of the KPRI, and allow projects to be competitive for the very best science on the national stage. A second, but important, goal is to ensure that a dedicated funding source is available to unique segments of the pediatric research and education.

 

Emily Smitherman, M.D.
Assistant Professor
Division of Pediatric Rheumatology
Project title: Adolescent Transfer to Adult Care—Rheumatology Patients

Mary Lauren Scott, M.D.
Associate Professor
Division of Pediatric Endocrinology & Diabetes
Project title: Improving Glycemic Control in High-risk Patients with Type I Diabetes

Ismail Mohamed, M.D.
Associate Professor
Division of Pediatric Neurology
Project title: Pediatric Epilepsy Learning Health System